It is important that you reload the data in your triple store, as well as consider the impact that the dependency changes may have on your customisations and integrations.

There are no ontology changes, and data produced by 21.10.0 is compatible with 1.6 - 1.9 (and vice versa). It is not required to upgrade to this release prior to subsequent releases. Please see Upgrading VIVO for more details.