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Changing MySQL’s transaction logging settings can lead to dramatic improvements to the speed at which triples are added to or removed from the database.  For more details, see „Writing the MySQL transaction log” here: MySQL configuration, tuning, and troubleshooting 

HTTP Caching

If VIVO's dynamically-generated pages do not exhibit acceptable load times, you may wish to enable HTTP caching.  See Use HTTP caching to improve performance.  With this configuration, subsequent requests for pages whose contents have not changed will be served directly from a cache instead of being regenerated from data in the triple store.

Additional discussion

Work in progress at https://docs.google.com/a/symplectic.co.uk/document/d/1ylp9HEzJiBsBP6vx1vd-Irf8o3Ff-5vDhytOVTI5_Ho/edit#heading=h.vdtjwwvnjdn7