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The Integrated Semantic Framework is maintained in a file repository (currently on Google code) that reflects the source ontologies while creating distribution modules grouping classes and properties more by function, such as grants, agents, education, etc.

Ontologies Integrated into the

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Integrated Semantic Framework

As documented on the CTSAconnect website ontologies page, the ISF ontology leverages the following ontologies in a unified, semantic structure:

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• Basic Formal Ontology (BFO) – http://www.ifomis.org/bfo
• Bibliographic Ontology (BIBO) – http://code.google.com/p/bibotools
• Cell Ontology (CL) – http://cellontology.org/?q=download
• Event Ontology – http://motools.sourceforge.net/event/event.html
• Friend of a Friend (FOAF) – http://www.foaf-project.org/
• Gene Ontology (GO) – http://geneontology.sourceforge.net/#code
• Geopolitical.owl, from the U.N. Food and Agriculture Organization
• Information Artifact Ontology (IAO) – http://code.google.com/p/information-artifact-ontology/
• Ontology for Biomedical Investigations (OBI) – http://obi.sourceforge.net/ontologyInformation/
• Ontology of Clinical Research (OCRe) – http://code.google.com/p/ontology-of-clinical-research/
• Relations ontology Ontology (RO) – http://obofoundry.org/ro/
• Software Ontology (SWO) – http://theswo.sourceforge.net/
• Sequence Ontology (SO) – http://www.sequenceontology.org/
• SKOS – http://www.w3.org/2004/02/skos/
• Uberon – http://obo.svn.sourceforge.net/viewvc/obo/uberon/releases/
• Vcard – http://www.w3.org/TR/vcard-rdf/